Logistic regression was used to identify predictors of response and Complete Response, and subgroups of patients who respond best to the capsaicin patch.īaseline pain intensity score (BPIS)≤4 was a predictor of Sustained and Complete Response in PHN and HIV-AN patients absence of allodynia and presence of hypoesthesia, and a McGill Pain Questionnaire (MPQ) sensory score <22 were predictors of Sustained Response in PHN patients female sex was a predictor of Sustained and Complete Response in HIV-AN patients. Sustained response was defined as>50% decrease in the mean pain intensity from baseline to weeks 2 to 12, and Complete Response as an average pain intensity score≤1 during weeks 2 to 12. We conducted a meta-analysis of 6 completed randomized and controlled Qutenza studies by pooling individual patient data. ![]() Our objective was to determine the baseline characteristics of patients who best benefit from capsaicin patch treatment. In clinical studies, some patients had a dramatic response to the capsaicin patch. ![]() Qutenza is a high-dose capsaicin patch used to relieve neuropathic pain from postherpetic neuralgia (PHN) and HIV-associated neuropathy (HIV-AN).
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